PEDIATRICS Vol. 53 No. 3 March 1974, pp. 446-447
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lubin, B. H.
Right arrow Articles by Murphy, S. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lubin, B. H.
Right arrow Articles by Murphy, S. B.

Letter to the Editor

Bertram H. Lubin M.D.1 and Sharon B. Murphy M.D.1

1 Fellow in Hematology and Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

The article, Anesthetic Risks in Sickle Cell Trait, is disconcerting because its conclusions are unjustified and its implications unwarranted. For example, due to the paucity of preoperative information one might conclude that the patients were doubly heterozyous for a hemoglobinopathy such as sickle thalassemia.

The presence of generalized sickling at postmortem exam in the five patients reported does not constitute proof that intravascular sickling was pathogenic in the patient's death, for it is obvious that red cells from a patient with sickle trait will assume the sickled shape in the acidotic and hypoxic postmortem state.