PEDIATRICS Vol. 52 No. 3 September 1973, pp. 416-419
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Phillips, C. F.
Right arrow Articles by Geraghty, M. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Phillips, C. F.
Right arrow Articles by Geraghty, M. E.

KILLED SUBUNIT INFLUENZA VACCINE IN CHILDREN

Carol F. Phillips M.D., FAAP1, Charles A. Phillips M.D.1, William E. Hodgkin M.D., FAAP1, Ben R. Forsyth M.D.1, Ben A. Rubin Ph.D.1, and Margaret E. Geraghty 1

1 Departments of Pediatrics and Medicine, University of Vermont College of Medicine, Burlington, Vermont, and Wyeth Laboratories, Inc., Marietta, Pennsylvania

Thirty-three children ranging in age from 5 to 9 years were immunized with varying doses of bivalent A2 (Hong Kong variant) B subunit influenza vaccine. The immunization was given intramuscularly. There were no local or systemic reactions. Thirty-one of 33 children (94%) demonstrated four-fold or greater rises in antibody titer to type A antigen. Twenty-one of 33 (64%) showed four-fold or greater rises to type B antigen. A booster four weeks after immunization produced no significant increase in antibody titer. The subunit influenza vaccine, which is antigenic and well tolerated in children, should be considered for use if routine immunization of children against influenza is deemed desirable.

Submitted on January 17, 1973
Accepted on March 19, 1973




This article has been cited by other articles:


Home page
 PediatricsHome page
A. Kempe, M. F. Daley, J. Barrow, N. Allred, N. Hester, B. L. Beaty, L. A. Crane, K. Pearson, and S. Berman
Implementation of Universal Influenza Immunization Recommendations for Healthy Young Children: Results of a Randomized, Controlled Trial With Registry-Based Recall
Pediatrics, January 1, 2005; 115(1): 146 - 154.
[Abstract] [Full Text] [PDF]