PEDIATRICS Vol. 52 No. 3 September 1973, pp. 382-387
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LINEAR NEVUS SEBACEOUS SYNDROME: REPORT OF TWO CASES AND A REVIEW OF THE LITERATURE

Frederick H. Lovejoy Jr. M.D.1 and William E. Boyle Jr. M.D.1

1 Department of Medicine, Children's Hospital Medical Center, and the Department of Pediatrics, Harvard Medical School, Boston, Massachusetts

Two cases of linear nevus sebaceous syndrome are described and a review of the eleven cases now reported in the literature is undertaken.

The first patient has retardation, seizures, and classic ectodermal lesions while the second patient manifests typical cutaneous lesions and only an elevated cerebrospinal fluid protein as evidence of neurologic disease. The rationale for defining the syndrome as an entity distinct from other neurocutaneous syndromes is discussed and a pleomorphic presentation of the syndrome is suggested.

Submitted on January 17, 1973
Accepted on March 9, 1973




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