PEDIATRICS Vol. 52 No. 1 July 1973, pp. 29-37
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THE INTERPLAY OF BIOLOGICAL AND ENVIRONMENTAL FACTORS IN A PRESCHOOL-AGE PATIENT WITH KLINEFELTER'S SYNDROME

Magda Campbell M.D.1, Harry Breuer M.A.1, and Sandra R. Wolman M.D.1

1 Department of Psychiatry and the Department of Pathology, New York University Medical Center

A 3-year-old male with 47XXY karyotype is presented as an example of how various genetic and environmental (including psychosocial) factors can contribute to delayed and/or disturbed behavior. The young preschool child's behavioral repertoire is so small, undifferentiated, and nonspecific that a variety of causes can evoke the same symptom(s) and behavior, and the danger of misdiagnosis, therefore, is great. Such disturbances may not be entirely or partially caused by a disturbed parent-child relationship. The pediatrician is usually the first to see such a young patient and in a position to initiate appropriate referrals for a complete diagnostic work-up, including cytological, hearing, and speech studies, not only for accurate diagnosis, but also for prognosis, treatment, and parental counseling.

Submitted on June 12, 1972
Accepted on December 18, 1972




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[Abstract]