PEDIATRICS Vol. 52 No. 1 July 1973, pp. 128-131
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Simple Device for Producing Continuous Negative Pressure in Infants With IRDS

Eduardo Bancalari M.D.1, Tilo Gerhardt M.D.1, and Ellen Monkus Ph.D., M.D.1

1 Department of Pediatrics, University of Miami School of Medicine, P.O. Box 875, Biscayne Annex, Miami, Florida 33152

Increasing experience with the use of continuous transpulmonary pressure, either positive or negative, during the last years has clearly demonstrated the success of this mode of therapy in IRDS.1-3

Forty newborn infants with this disease have been treated with continuous negative pressure (CNP) in the Newborn Intensive Care Unit, Department of Pediatrics, University of Miami School of Medicine, using a modified incubator-respirator.*

Twenty-one required only CNP, three of whom died (14%). Among the 19 who needed CNP plus intermittent positive pressure ventilation, nine died (47%). All required more than 70% oxygen to maintain a Pao2 over 50 mm Hg before using CNP.




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Eur. Respir. J., July 1, 2002; 20(1): 187 - 197.
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