1 University of California, San Diego, P.O. Box 109, La Jolla, California 92037
When the "Collaborative Study"1 was conceived it was undertaken with the hope of obtaining definitive answers to some complex questions in the field of obstetrics and perinatology. It could be anticipated that, by the meticulous collection of data on prenatal, natal, and postnatal events in thousands of pregnancies, indisputable evidence might be gained as to certain causes of mental retardation, birth defects, infectious complications of pregnancy, and the like. Ultimately, it was hoped that the application of such evidence might lead to measures for prevention.
The study was enormous. An incredible amount of data still awaits analysis. The paper by Froehlich and Fujikura1 in this issue is but one small step toward the realization of the goals originally set.