1 Department of Pediatrics U.S. Army General Hospital Fort Gordon, Georgia 30905
Quick1 states that spontaneous intracranial hemorrhage is less common in hemophilia than in other clotting disorders, though others2-3 have shown it to occur in as high as 10% to 13% of all cases of hemophilia. However, intracranial hemorrhage is an exceedingly rare occurrence in the neonate with hemophilia.4-5 Silverstein's review of 31 reported cases of proven hemophilia with intracranial hemorrhages revealed only one case in the neonatal period. The advent of readily available and definitive laboratory procedures for the prompt diagnosis of hemophilia coupled with the development of factor VIII concentrates allows for the aggressive treatment of intracranial hemorrhages and their complications.
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B.P. Sachs, D. Acker, R. Tuomala, and E. Brown The Incidence of Symptomatic Intracranial Hemorrhage in Term Appropriate-for-gestation-age Infants Clinical Pediatrics, July 1, 1987; 26(7): 355 - 358. [Abstract] [PDF] |
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