PEDIATRICS Vol. 50 No. 6 December 1972, pp. 923-925
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Continuous Antibiotic Therapy in Chronic Granulomatous Disease: Preliminary Communication

Arvin I. Philippart M.D.1, Arnold H. Colodny M.D.1, and Robert L. Baehner M.D.1

1 Departments of Surgery and Medicine, Children's Hospital Medical Center, Departments of Surgery and Pediatrics, Harvard Medical School, Boston, Massachusetts

A series of nine patients with chronic granulomatous disease have been maintained on continuous nafcillin therapy for a period adequate to allow preliminary evaluation. Clinically significant hepatic sepsis has not occurred since initiation of this program. The effect on extra-hepatic sepsis is not yet clearly established.