PEDIATRICS Vol. 50 No. 5 November 1972, pp. 723-727
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CHANGING INCIDENCE OF HEMOPHILUS INFLUENZAE MENINGITISX

Edward W. P. Smith Jr. M.D.1 and Ralph E. Haynes M.D.1

1 Departments of Pediatrics and Medical Microbiology, Ohio State University College of Medicine, and the Columbus Children's Hospital

We studied the incidence of Hemophilus influenzae meningitis at the Columbus Children's Hospital (CCH) during the following intervals: Period A (1942 to 1950), Period B (1951 to 1959), and Period C (1960 to 1968).

Other investigators have reported an increase in the incidence of influenzal meningitis, but there has been no predictable relationship to the number of hospial admissions. Thre was a 399% increase in the number of patients with H. influenzae meningitis at the CCH from Period A to Period C, roughly proportional to the rise in total hospial admissions during he same time.

Children under 5 years of age constitute the major population at risk. Incidence stated in terms of population at risk appears to be a reliable method of comparing experience in specific geographic areas during specific periods of time. The experience at the CCH, using this method, indicates a significant increase in this disease without comparable increases in meningitis caused by other bacteria.

Submitted on March 6, 1972
Accepted on May 19, 1972




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