PEDIATRICS Vol. 5 No. 5 May 1950, pp. 883-887
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HERPES SIMPLEX VIRUS NOT THE ETIOLOGIC AGENT OF RECURRENT STOMATITIS

KATHARINE DODD M.D.1 and ISAAC RUCHMAN Ph.D.1

1 The Children's Hospital Research Foundation and the Departments of Pediatrics and Bacteriology, University of Cincinnati College of Medicine, Cincinnati, Ohio.

The virus of herpes simplex is not the usual etiologic agent of recurrent aphthous or ulcerative stomatitis.

In reported cases in which the herpes virus has been recovered from the mouths of individuals suffering from recurrent stomatitis or the titer of antibodies has risen in the blood serum following infection, it seems probable that these were chance findings which bore no relation to the etiology of the disease.