PEDIATRICS Vol. 49 No. 1 January 1972, pp. 149
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Prognosis with X-Chromosomal Abnormalities: Neoplastic Disease

Doris Bartuska M.D.1 and Linda Vardaro M.D.1

1 The Medical College of Pennsylvania, 3300 Henry Avenue, Philadelphia, Pennsylvania 19129

The report of Eller, et al. on the prognosis in newborn infants with X-chromosomal abnormalities prompts this note.

Because of our interest in cytogenetic factors in carcinogenesis, a routine buccal smear for sex chromatin is performed on all our patients with amenorrhea or irregular vaginal bleeding.

Recently a 26-year-old woman with dysmenorrhea and irregular periods was seen. She had a mass arising from the cervix which was subsequently diagnosed as an unusual exophytic type of squamous cell carcinoma.