PEDIATRICS Vol. 48 No. 6 December 1971, pp. 907-913
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A SEX DIFFERENCE IN THE CARRIER STATE OF AUSTRALIA (HEPATITIS-ASSOCIATED) ANTIGEN

Morris Goodman Ph.D.1, Robert L. Wainright B.S.1, Homer F. Weir M.D.1, and John C. Gall Jr. M.D.1

1 Plymouth State Home and Training School, Northville, Michigan

A survey of 1,077 mentally retarded residents of Plymouth State Home and Training School for the distribution of Australia (hepatitis-associated) antigen and precipitins to this antigen revealed that karyotypically normal females show a much lower prevalence of the antigen than do the males, whereas among young G-trisomic patients the females as well as males show a high prevalence of the antigen. Early age of institutionalization increases the risk of becoming an Australia antigen carrier, but less so in karyotypically normal females than in other groups.

Submitted on March 8, 1971
Accepted on June 7, 1971




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J. Drew, W. London, E. Lustbader, J. Hesser, and B. Blumberg
Hepatitis B virus and sex ratio of offspring
Science, August 25, 1978; 201(4357): 687 - 692.
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