PEDIATRICS Vol. 48 No. 4 October 1971, pp. 642-646
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Double-Blind Trial of Aminophylline in Status Asthmaticus

William E. Pierson M.D.1, C. Warren Bierman M.D.1, Stanley J. Stamm M.D.1, and Paul P. VanArsdel Jr. M.D.1

1 Departments of Pediatrics and Medicine, University of Washington School of Medicine, Children's Orthopedic Hospital and Medical Center, Seattle, Washington 98105

Significant improvement in ventilatory function without observable adverse effects has been demonstrated by this double-blind controlled trial of intravenous aminophylline in status asthmaticus. Aminophylline appears to have a beneficial therapeutic effect when given in addition to other accepted medications in appropriate dosage and under careful medical supervision to hospitalized children with status asthmaticus.




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