PEDIATRICS Vol. 48 No. 4 October 1971, pp. 601-604
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Rule, A. H.
Right arrow Articles by Shwachman, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Rule, A. H.
Right arrow Articles by Shwachman, H.

IgA: PRESENCE IN MECONIUM OBTAINED FROM PATIENTS WITH CYSTIC FIBROSIS

Allyn H. Rule Ph.D.1, David Lawrence M.S.1, Hans J. Hager Ph.D.1, Newton Hyslop Jr. M.D.1, and Harry Shwachman M.D.1

1 Graduate Department of Biology, Boston College, Chestnut Hill, Massachusetts; Hoffmann-La Roche Inc., Research Division, Nutley, New Jersey; Massachusetts General Hospital; Children's Hospital Medical Center and Harvard Medical School, Boston

Meconiums obtained from patients with cystic fibrosis (CF) have been found to contain secretory and/or serum IgA.

Since IgA is believed to be synthesized after birth, its presence in the prenatal gut of patients with a hereditary disease involving dysfunction of the exocrine glands may be related to the basic disease lesion.

Submitted on July 30, 1970
Accepted on March 13, 1971