PEDIATRICS Vol. 48 No. 4 October 1971, pp. 583-594
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THE GROWTH AND DEVELOPMENT OF FOUR XYY INFANTS

G. H. Valentine M.B., M.R.C.S.(Eng.), F.R.C.P.(C)1, Marilyn A. McClelland M.A.1, and F. R. Sergovich Ph.D1

1 War Memorial Children's Hospital, Crippled Children's Treatment Centre and Children's Psychiatric Research Institute, London, Ontario

Four XYY infants ascertained from 1,066 unselected newborn infants have been followed for 2frac12 to 3frac12 years. None of them show any distinctive physical characteristics, though three of the four lack a C triradius in the palmar dermatoglyphics. All four are of normal stature. Three appear of normal intellect and personality. One is of borderline intelligence and by 2 years was exhibiting aggressive, defiant, and destructive behavior.

There are great problems of what, if anything, to divulge to the parents when an XYY chromomosome complement has been discovered.

Submitted on December 14, 1970
Accepted on March 1, 1971




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