PEDIATRICS Vol. 48 No. 4 October 1971, pp. 540-546
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LIPID CONCENTRATION AND COMPOSITION IN HUMAN FETAL TISSUE DURING DEVELOPMENT

Jacques F. Roux M.D.1, Y. Takeda M.D.1, and A. Grigorian 1

1 Department of Reproductive Biology, Case Western Reserve University School of Medicine, Cleveland, Ohio and the Perinatal Clinical Research Center at Cleveland Metropolitan General Hospital, Cleveland, Ohio and the Department of Obstetrics and Gynecology, Okayama University Medical School, Okayama, Japan

The concentration and fatty acid composition of lipids from the sixth to thirty-second week of gestation has been measured in human fetal tissues.

The data found show that the lipid concentration and fatty acid composition does not vary significantly during these stages of development. However, more palmitic acid and less linoleic acid is detected in fetal adipose tissue than in that of the mother and this relationship does not change in the immediate postpartum period. The results suggest that fetal lipid metabolism is well established early in gestation and that the concentration of lipids increases in proportion to the rate of growth of the fetal organs and cell structure.

Submitted on October 19, 1970
Accepted on March 5, 1971




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