PEDIATRICS Vol. 48 No. 1 July 1971, pp. 51-58
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INTUSSUSCEPTION IN PATIENTS WITH CYSTIC FIBROSIS

Douglas S. Holsclaw M.D.1, Claude Rocmans M.D.1, and Harry Shwachman M.D.1

1 Division of Clinical Laboratories and Departments of Medicine, The Children's Hospital Medical Center and the Department of Pediatrics, Harvard Medical School, Boston, Massachusetts

Intussusception is one of the lesser known intestinal complications of cystic fibrosis and occurs in approximately 1% of patients. Clinical details are presented of 22 episodes of intussusception occurring in 19 patients over 4 years of age. The average age at onset was 9 9/12 years (Range 4 to 16 years). Most patients were in good or excellent clinical condition and all had pancreatic insufficiency. An operation was performed for 19 of the 22 episodes; resection was required twice. The etiology of the intussusception was felt to be the accumulation of thick putty-like inspissated material in the cecum. Reasons are given for urging the judicious use of the barium enema as a means of reducing the intussusception. Intussusception occurs more frequently than commonly thought and may even be the presenting complaint of the undiagnosed patient with cystic fibrosis.




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