PEDIATRICS Vol. 47 No. 6 June 1971, pp. 1019-1022
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AN UNIQUE PRESENTATION OF SICKLE CELL DISEASE:PYOGENIC HEPATIC ABSCESS

Stanford T. Shulman M.D.1 and Marc O. Beem M.D.1

1 Department of Pediatrics, University of Chicago, Chicago, Illinois

A laparotomy-proved pyogenic hepatic abscess was the initial clinical manifestation of sickle cell disease in a 4-year-old black boy. Although this complication has been reported in an adult patient with sickle cell disease, it has not been reported previously in children nor as the presenting manifestation of this state. Peptococcus species, a strictly anaerobic staphylococcus never previously reported implicated in a liver abscess, was isolated from two blood cultures. Inadequate anaerobic bacteriologic techniques may explain the failure to identify the causative organism in up to 60% of pyogenic hepatic abscesses. That this abscess represents a secondarily-infected hepatic sickle cell infarction seems probable.

Submitted on October 13, 1970
Accepted on December 28, 1970


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