1 Department of Pediatrics, Sapporo Medical College, S.1 W.16, Sapporo, Japan
Seventy-one patients with two or three attacks of aseptic meningitis were seen during the 16-year period, 1953-1968, when a total of 1,956 patients with that disease were observed. All were under 15 years of age. The interval between attacks ranged from a month to 4 years. Clinical and laboratory findings of sequential attacks did not differ. Virological data were available from both of two attacks in 11 patients. These data indicate that a person may be attacked with aseptic meningitis more than once; usually the causative virus is different in subsequent attacks.