PEDIATRICS Vol. 47 No. 3 March 1971, pp. 594-598
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Zollinger-Ellison Syndrome in a Nineyear -old Child: A Case Report and Review of this Entity in Childhood

Richard M. Buchta 1 and J. M. Kaplan 2

1 MC, USN, Department of Pediatrics, Naval Hospital, Camp Pendleton, California 92055
2 LCDR, MC, USNR, Department of Pediatrics, Naval Hospital, Camp Pendleton, California 92055

In 1955, Zollinger and Ellison1 described a syndrome consisting of peptic ulceration, marked gastric hypersecretion, and non-beta islet cell tumor of the pancreas.

Although there have been over 300 cases in the adult literature2-5 only 19 patients, 16 years old or younger have been reported. We add one more child to this growing list and review the clinical data of the known cases described.

Case Report

The patient (R.L.) was a 9-year-old Negro male with a 7-month history of intermittent episodes of mid-epigastric abdominal pain. The pain was somewhat relieved by eating, or the use of antispasmodics. During this period of time, the child had occasional episodes of vomiting, but no melena or hematemesis.