PEDIATRICS Vol. 47 No. 3 March 1971, pp. 510-515
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IODIDE GOITER IN THE NEWBORN

Boris Senior M.D.1 and Harvey L. Chernoff M.D.1

1 Pediatric Endocrine-Metabolic and Pediatric Cardiology Services of the Tufts-New England Medical Center Hospitals (Boston Floating Hospital for Infants and Children), Boston, Massachusetts

A hyperthyroid mother, treated with potassium iodide, gave birth to a baby with an enormous goiter. The infant, although hypothyroid, had massive cardiomegaly and high output failure due to a shunt across the vessels of the goiter. Administration of thyroid caused shrinkage of the gland and concomitantly the heart became smaller. The infant then developed hyperthyroidism which persisted for several months.

The late stage of onset of hyperthyroidism in the infant, the inability to demonstrate LATS in mother or child, and the resemblance to other reported cases of iodide goiter in infancy together indicate that the hyperthyroidism may have been a consequence of the iodide goiter rather than a result of the transmission of LATS from the hyperthyroid mother.

Submitted on May 11, 1970
Accepted on October 29, 1970