PEDIATRICS Vol. 47 No. 1 January 1971, pp. 88-93
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NEUTRON ACTIVATION ANALYSIS TECHNIQUE FOR NAIL SODIUM CONCENTRATION IN CYSTIC FIBROSIS PATIENTS

G. Frank Johnson M.D.1, Max F. Thompson M.N.E.1, S. Fetteroff M.S.1, and A. N. Fasano M.C.E1

1 Department of Radiology, Barney Children's Medical Center and the Air Force Institute of Technology, Dayton, Ohio

This study reports nail sodium values in milliequivalents per kilogram as determined by neutron activation analysis in a variety of normal, hospitalized, and cystic fibrosis children. The elevated sodium values thus determined in cystic fibrosis indicate the usefulness of the method, though they are not in themselves diagnostic.

The nails are porous to sodium and reflect the sweat sodium levels. The results are influenced by age, environment of the nail, and other disease conditions.

Submitted on October 6, 1969
Accepted on June 30, 1970