PEDIATRICS Vol. 47 No. 1 January 1971, pp. 125-128
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Agathopoulos, A.
Right arrow Articles by Papadatos, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Agathopoulos, A.
Right arrow Articles by Papadatos, C.

Biochemical Changes of Catechol-O-Methyltransferase During Development of Human Liver

A. Agathopoulos M.S.1, D. Nicolopoulos M.D.1, N. Matsaniotis M.D.1, and C. Papadatos M.D.1

1 Pediatric Clinic of Athens University Athens, Greece

COMT is found in human liver before birth and its activity increases with age until the sixth decade. There is also evidence of change in properties of the enzyme within adult age Fig. 2) . The increased amounts of metacate-cholamines and VMA excreted during the first day of life in the urine of full-term versus premature infants18 and, still more, in the urine of adults, if compared to newborn, could be attributed to the increased COMT activity with advancing age.




This article has been cited by other articles:


Home page
 Cereb CortexHome page
E. Tunbridge, C. Weickert, J. Kleinman, M. Herman, J Chen, B. Kolachana, P. Harrison, and D. Weinberger
Catechol-o-Methyltransferase Enzyme Activity and Protein Expression in Human Prefrontal Cortex across the Postnatal Lifespan
Cereb Cortex, May 1, 2007; 17(5): 1206 - 1212.
[Abstract] [Full Text] [PDF]