PEDIATRICS Vol. 46 No. 6 December 1970, pp. 933-936
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The Frequency of Asymptomatic Hypoglycemia in High Risk Newborn Infants

Richard Guthrie M.D.1, G. Van leeuwen M.D.2, and Linda Glenn B.A.2

1 Department of Pediatrics, University of Missouri, College of Medicine, Columbia, Missouri 65201
2 Department of Pediatrics, University of Nebraska, College of Medicine, 42nd and Dewey Avenue Omaha, Nebraska 68105

Serial blood glucose determinations were performed on 109 high risk and 25 normal term infants. Eight of these risk infants (7.3%) had at least two glucose determinations of less than 20 mg/100 ml; 20 (18%) had at least one determination less than 20 mg/100 ml. Although no documented clinical significance of transient asymptomatic hypoglycemia is known to date, it occurs very frequently in high risk infants. Therefore, we advocate that the current practice of very early oral or intravascular feeding in risk infants be continued.