PEDIATRICS Vol. 46 No. 4 October 1970, pp. 647
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Letter To The Editor

Jerome O. Klein M.D.1

1 Associate Professor of Pediatric Harvard Medical School

Dr. Strauss has concisely summarized present considerations of the role of encapsulated and nonencapsulated Hemophilus influenzae in infection and disease. A recent clinical review by Turk and May1 documents the predominance of Hemophilus influenzae type B in suppurative disease. In a survey of reports of cases of meningitis due to this agent, the authors found only 24 cases due to Hemophilus influenzae other than type B(type A = 6, type E = 1, type F = 3, and non-typable 14). The role of nonencapsulated Hemophilus influenzae strains in the pathogenesis of respiratory infections and otitis media is still unclear. The majority of H. influenzae strains isolated from the middle ear fluids of children with acute otitis media are nonencapsulated.2,3