PEDIATRICS Vol. 46 No. 4 October 1970, pp. 548-552
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BENIGN PERSISTENT ASYMPTOMATIC PROTEINURIA IN CHILDHOOD

Peter N. McLaine M.D., F.R.C.P.(C)1 and Keith N. Drummond M.D., C.M., F.R.C.P.(C)1

1 Renal Laboratory, McGill University-Montreal Children's Hospital Research Institute, Montreal, Canada

Persistent asymptomatic proteinuria was detected by routine urinalysis in six children. The mean 24-hour protein excretion was less than 2 gm. Renal biopsy showed no abnormal findings except for minor focal mesangial changes in one; there was no glomerular deposition of immunoglobulin G, betaio globulin, or fibrin. No evidence of progressive nephropathy was detected over a mean follow-up period of 4.6 years.

It is recognized that persistent asymptomatic proteinuria occurs during the course of various renal diseases in children; however our experience with patients in whom proteinuria is the sole presenting feature is that the majority have a benign condition.

Submitted on October 31, 1969
Accepted on May 14, 1970




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E. C. Burke and G. B. Stickler
Proteinuria in Children: Review and Evaluation
Clinical Pediatrics, December 1, 1982; 21(12): 741 - 743.
[Abstract] [PDF]