1 Department of Pediatrics, Children's Hospital of the District of Columbia and George Washington University, School of Medicine, 2125 13th Street, N.W., Washington, D.C. 20009
A newborn infant with cardiac failure resulting from a rhabdomyoma of the left ventricle obstructing the aortic outflow tract is described. Mild subvalvular pulmonary stenosis was also present because of a tumor in the ventricular septum. Tuberous sclerosis occurs in at least half of infants with such tumors and was present pathologically in this child, although not apparent clinically.
Rhabdomyomas must be considered in the differential diagnosis of heart disease in the newborn infant and may be associated with tuberous sclerosis even when nervous system and cutaneous signs are not present.
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A. L. Alkalay, D. A. Ferry, B. Lin, B. W. Fink, and J. J. Pomerance Spontaneous Regression of Cardiac Rhabdomyoma in Tuberous Sclerosis Clinical Pediatrics, October 1, 1987; 26(10): 532 - 535. [PDF] |
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