PEDIATRICS Vol. 46 No. 3 September 1970, pp. 389-396
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sachs, H. K.
Right arrow Articles by O'Connell, M. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sachs, H. K.
Right arrow Articles by O'Connell, M. J.

AMBULATORY TREATMENT OF LEAD POISONING: REPORT OF 1,155 CASES

Henrietta K. Sachs M.D.1, Lorry A. Blanksma Ph.D.1, Edward F. Murray M.D.1, and Morgan J. O'Connell M.D1

1 Lead Poisoning Clinic, Chicago Board of Health

Subjects with lead concentrations greater than 50 µg per 100 ml whole blood were referred to a municipal lead poisoning clinic for evaluation. Chelating agents were administered when two blood lead levels were more than 50 µg, or calcium disodium edetate (EDTA) provocative test yielded over 1,000 µg/l of lead in the urine in the succeeding 8 hours. Therapy was on an ambulatory basis. Patients with moderate encephalopathy were hospitalized. Intramuscular EDTA, oral penicillamine, or the two drugs in sequence were given to 582 patients in 1967 and to 573 patients in 1968. Clinical evidence of lead intoxication was present in 103 or 8.9% of the 1,155 patients. Several drug reactions to penicillamine were observed, but none to EDTA, and mortality dropped due to early detection and detoxification of subclinical cases of lead poisoning.

Submitted on September 11, 1969
Accepted on April 23, 1970




This article has been cited by other articles:


Home page
 Behav ModifHome page
C. R. Johnson, F. M. Hunt, and M. J. Siebert
Discrimination Training in the Treatment of Pica and Food Scavenging
Behav Modif, April 1, 1994; 18(2): 214 - 229.
[Abstract]

Home page
 CLIN PEDIATRHome page
M. E. Mortensen and P. D. Walson
Chelation Therapy for Childhood Lead Poisoning: The Changing Scene in the 1990s
Clinical Pediatrics, May 1, 1993; 32(5): 284 - 291.
[PDF]

Home page
 Topics in Early Childhood Special EducationHome page
F. M. Hunt, C. R. Johnson, G. Owen, A. J. Ormerod, and R. L. Babbitt
Early Intervention for Severe Behavior Problems: The Use of Judgment-Based Assessment Procedures
Topics in Early Childhood Special Education, January 1, 1990; 10(3): 111 - 121.
[Abstract] [PDF]

Home page
 CLIN PEDIATRHome page
N. Putnam and M. Stein
Self-inflicted Injuries in Childhood: A Review and Diagnostic Approach
Clinical Pediatrics, September 1, 1985; 24(9): 514 - 518.
[Abstract] [PDF]

Home page
 CLIN PEDIATRHome page
G. J. Cohen
Lead Poisoning: 20 Years Later
Clinical Pediatrics, April 1, 1980; 19(4): 245 - 250.
[Abstract] [PDF]