PEDIATRICS Vol. 45 No. 4 April 1970, pp. 640-650
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CONGENITAL HEART BLOCK DUE TO A LESION IN THE CONDUCTION SYSTEM

Cirilo Sotelo-Avila M.D.1, Harvey S. Rosenberg M.D.1, and Dan G. McNamara M.D.1

1 Departments of Pathology and Pediatrics, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas

The cardiac conduction system of an infant with congenital complete heart block was studied at postmortem examination by subserial sections of the interatrial and interventricular septa. A localized area of necrosis in the central fibrous body interrupted the penetrating portion of the bundle of His. The cardiac structure was intact, with no abnormality other than the lesions in the fibrous tissue. The lesion is interpreted as the result of an acquired inflammation late in intrauterine life, with damage localized to the cardiac central fibrous body.

Submitted on August 28, 1969
Accepted on November 29, 1969