PEDIATRICS Vol. 44 No. 6 December 1969, pp. 991-998
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THE CRITICALLY ILL CHILD: MANAGEMENT OF ACUTE BACTERIAL MENINGITIS

Paul F. Wehrle M.D.1, Allen W. Mathies Jr. M.D.1, and John M. Leedom M.D.1

1 Departments of Pediatrics and Medicine, University of Southern California School of Medicine, the Communicable Disease Service, Los Angeles County-University of Southern California Medical Center, and the Hastings Foundation Infectious Disease Laboratory

The presently available, effective antimicrobial therapy has substantially decreased the frequency of disability due to meningitis and has been even more effective in reducing mortality. Optimum therapeutic results are dependent upon prompt clinical recognition of disease, the specific identification of the infectious agent, the prompt administration of bactericidal drugs by the intravenous route, and proper monitoring of the patient during the acute illness. Indeed, rapid diagnosis, monitoring the patient for shock with prompt restoration of effective circulation, early detection of complications, and proper concern toward rehabilitative measures are features of therapy which may be as important as choosing the right antimicrobial.




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