PEDIATRICS Vol. 42 No. 5 November 1968, pp. 786-792
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FAMILIAL NONHEMOLYTIC JAUNDICE WITH LATE ONSET OF NEUROLOGICAL DAMAGE

Sarah D. Blumenschein M.D.1, Ronald J. Kallen M.D.1, Bruce Storey M.D.1, Jürgen C. Natzschka M.D.1, Gerald B. Odell M.D.1, and Barton Childs M.D.1

1 Department of Pediatrics of the Johns Hopkins University School of Medicine and the Harriet Lane Service of the Johns Hopkins Children's Medical and Surgical Center, Baltimore

A patient with familial nonhemolytic jaundice is described. The child had been normal, apart from his jaundice, for all of his life. But, at 16 years of age he developed neurological disabilities which progressed to his death 6 months later. The signs were similar to those of kernicterus seen in infants. Attempts to reduce the bilirubin level of the blood and so to reverse the nervous system damage were unsuccessful.

Submitted on January 15, 1968
Accepted on June 24, 1968




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