PEDIATRICS Vol. 42 No. 4 October 1968, pp. 678-683
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Pietra, G. G.
Right arrow Articles by Braudo, J. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Pietra, G. G.
Right arrow Articles by Braudo, J. L.

Electron Microscopy of Cutaneous Capillaries of Newborn Infants: Effects of Placental Transfusion

Giuseppe G. Pietra M.D.1, Mabel D. D'Amodio M.D.1, Monika M. Leventhal B.S.1, William Oh M.D.1, and J. Leonard Braudo M.D.1

1 Departments of Pathology and Pediatrics, Michael Reese Hospital and Medical Center, 29th Street and Ellis Avenue, Chicago, Illinois 60616

Two hundred and ten capillaries taken by punch biopsy at 2 to 5 hours of age from term, normal, newborn infants were examined by electron microscopy. Six infants had early cord clamping and five had late cord ligation. In the late-clamped group, the capillaries were more distended morphologically as shown by a smaller endothelial index (endothelial area/total capillary area). In comparison to the early-clamped group, the late-clamped infants also had a larger number of fenestrated small blood vessels. Since fenestration is an anatomical structure related to rapid fluid exchange, it is suggested that this finding is an indication of a more active fluid transudation from the intravascular to the extravascular compartment in the late-clamped infants in response to a greater circulatory volume deriving from placental blood transfusion at birth. It is also suggested that the large number of fenestrated vessels in the late-clamped infants is a result of an increased number of openings of arteriovenous communications.




This article has been cited by other articles:


Home page
 PediatricsHome page
J. S. Mercer, B. R. Vohr, M. M. McGrath, J. F. Padbury, M. Wallach, and W. Oh
Delayed Cord Clamping in Very Preterm Infants Reduces the Incidence of Intraventricular Hemorrhage and Late-Onset Sepsis: A Randomized, Controlled Trial
Pediatrics, April 1, 2006; 117(4): 1235 - 1242.
[Abstract] [Full Text] [PDF]

Home page
 CLIN PEDIATRHome page
T. R. C. Sisson
The Placental Transfusion
Clinical Pediatrics, May 1, 1972; 11(5): 251 - 252.
[PDF]