PEDIATRICS Vol. 42 No. 4 October 1968, pp. 659-666
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GENITAL INFECTION WITH HERPESVIRUS HOMINIS TYPES 1 AND 2 IN CHILDREN

André J. Nahmias M.D.1, Walter R. Dowdle Ph.D.1, Zuher M. Naib M.D.1, William E. Josey M.D.1, and Carolyn F. Luce B.S.1

1 Departments of Pediatrics, Preventive Medicine, Pathology and Obstetrics-Gynecology, Emory University School of Medicine and Grady Memorial Hospital, and the Respiratory Infections Unit, Laboratory Program, National Communicable Disease Center, Public Health Service, Bureau of Disease Prevention and Environmental Control, United States Department of Health, Education and Welfare, Atlanta, Georgia

Five cases of genital infections with Herpesvirus hominis (HVH) in 7- to 12-year-old girls and one case in a 3-year-old boy have been observed over a 3-year period. HVH type 1 was isolated from the genital lesions and mouth in both the boy, who had no oral lesions, and in an 8-year-old girl with associated gingivostomatitis. The boy showed serological evidence of a type 1 HVH reinfection and the girl showed evidence of a primary type 1 infection. Laboratory studies on the other four girls confirmed a primary type 2 HVH infection.

On the basis of the virological, serological, and epidemiological information, it appears that genital infections with HVH in children can be either venereally or non-venereally transmitted. The physician should therefore use caution in his judgment as to the way in which a herpetic genital infection was acquired in his patient.

Submitted on January 25, 1968
Accepted on April 18, 1968




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