1 Newborn Service and the Department of Pathology, Children's Hospital of the District, of Columbia, Washington, D.C.
Shigellosis has been considered an infection usually limited to the mucosa and lumen of the large bowel with occasional involvement of regional lymph nodes. This is undoubtedly true in most cases, but well documented instances of bacteremia associated with severe systemic illnessl-5 suggest that significant blood stream invasion can occur. In the majority of cases the bacteremia was due to Shigella fiexneri or Shigella dysenteriae.
Three cases of Shigella sonnei septicemia in children6-8 and one case in an adult9 have been reported. Recently, the first case report of meningitis and septicemia due to this organism in a newborn infant was published.10
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B. Emanuel and J. O. Sherman Shigellosis in a Neonate: Successful Treatment with an Oral Elemental Diet Clinical Pediatrics, August 1, 1975; 14(8): 725 - 726. [PDF] |
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