1 Department of Pediatrics, Harvard Medical School, and the Sharon Cardiovascular Unit of the Children's Hospital Medical Center, Boston
Administration of intravenous ethacrynic acid in doses of 1 mg/kg to 8 study patients and 14 "nonstudy" patientsall of whom had congestive heart failureis reported. No significant changes in serum electrolytes are noted following administration of the drug. In nearly all cases, diureses and clinical improvement within a few hours after administration were noted. The authors suggest that intravenous ethacrynic acid replace mercurials in the treatment of acute congestive heart failure in infants and children.
Submitted on December 7, 1967
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D. Z. Friedberg and S. B. Litwin Cardiology Review : The Medical and Surgical Management of Patients with Congenital Heart Disease: A Survey of Current Knowledge and Practices Clinical Pediatrics, April 1, 1976; 15(4): 324 - 333. [Abstract] [PDF] |
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