1 Mayo Clinic, Rochester, Minnesota
We continue to agree with Dr. Nellhaus1 concerning the clinical value of the measurement of head circumference in children. Since publication of the paper by O'Connell and colleagues2 the opportunity has presented at the Mayo Clinic to study in detail a group of 15 children with idiopathic hypopituitary dwarfism. It was generally agreed that the children with this type of growth failure and normal intelligence do not have head circumferences of less than -2 standard deviations (S.D.).