1 Department of Pathology, University of Miami School of Medicine, the Mount Sinai Hospital, Miami Beach, Florida; the Department of Pathology, the University of Puerto Rico; and the Puerto Rico Medical Center, San Juan
Three main theories have to be considered in the pathogenesis of congenital pulmonary lymphangectasis: obstruction of major pulmonary lymphatics, obstruction to pulmonary venous flow, and anomalous pulmonary development. The authors report an infant with congenital pulmonary lymphangiectasis associated with a blind common pulmonary vein. Previously reported cases of congenital pulmonary lymphangiectasis associated with cardiac lesions causing obstruction to pulmonary venous flow are reviewed. This association appears too frequently to be merely coincidental. Obstruction to pulmonary venous flow provides a cause for the persistence of prominent fetal lymphatic channels and thus seems of pathogenetic importance in some cases of congenital pulmonary lymphangiectasis.
Submitted on October 25, 1967
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S. R. Kandall Congenital Pulmonary Lymphangiectasis: An Emerging Spectrum of Neonatal and Infantile Lung Disease Clinical Pediatrics, February 1, 1972; 11(2): 107 - 111. [PDF] |
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