PEDIATRICS Vol. 41 No. 3 March 1968, pp. 664-666
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Sex Chromatin Survey in 3,000 Newborn Infants in Mexico

Héctor Márquez-Monter M.D.1, Alessandra Carnevale-López M.D.2, and Susana Kofman-Alfaro M.D.3

1 Departamento de Investigación y Enseñanza, Centro Médico Nacional, I.M.S.S., Cuauhtémoc 330, México 7, D.F. México
2 Unidad de Patología, Hospital General de México
3 Departamento de Investigación y Enseñanza, Centro Médico Nacional, I.M.S.S.

A survey of sex chromatin was carried out in 3,000 newborn children at the General Hospital of Mexico City; 1,484 were males and 1,516 were females. In the male group 4 infants (0.26%) had positive chromatin and were considered to have a possible XXY or XXYY constitution. In the female group 3 infants (0.19%) did not show sex chromatin and were possible carriers of an XO complement. No correlation was found between the maternal age and number of pregnancies and the discrepant children. A comparison was made between the results obtained in this study and similar studies carried out in other countries. Fourteen instances of congenital abnormalities were found in this study; Down's syndrome was the most frequent (1/750-0.13%).


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