PEDIATRICS Vol. 41 No. 2 February 1968, pp. 381-382
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"PRECLINICAL" AND "CLINICAL" EVIDENCE

William A. Silverman M.D.1

1 Babies Hospital, 3975 Broadway, New York, New York 10032

Most of the pages in Pediatrics are reserved for original descriptions of a wide variety of phenomena which interest those concerned with the health of children. Advanced technics of biologic investigation are used increasingly to study these natural events in minute detail and at various levels (often subcellular) of organization. As a result, readers are now presented with much basic ("preclinical") evidence which provides the foundation for improved understanding of many outstanding problems in clinical pediatrics. Since there has been some discussion about the apportionment of space in Pediatrics between "preclinical" and "clinical" reports, it is appropriate to comment on some aspects of this particularly artificial dichotomy.