1 Department of Paediatrics, University of Toronto, Hospital for Sick Children, Toronto, Ontario
We have read with interest and admiration the recent paper by Drs. Lombroso and Lerman on breathholding spells (Pediatrics, 39:563, 1967) which does much to delineate the common cyanotic variety from the rare pallid variety. We wish to take issue, however, with their pathophysiologic considerations in the cyanotic variety and in particular with the "plausible combination of factors" leading to the attack (p. 575). No one would disagree with (2)apnea leading to hypoxemia; but surely it is unnecessary to go further than this.