1 Children's Hospital, Buffalo, New York 14222
2 Department of Pediatrics, Harvard Medical School and Children's Service, Massachusetts General Hospital, Boston, Massachusetts
A cretinous infant exhibited prolonged neonatal jaundice which subsided on thyroid replacement therapy. Accidental withdrawal of treatment with recrudescence of jaundice and a second drop in bilirubin on restoration of thyroid treatment served to document the close association of thyroid insufficiency and unconjugated hyperbilirubinemia.