PEDIATRICS Vol. 40 No. 2 August 1967, pp. 184-187
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PROLONGED HYPERTENSION FOLLOWING CESSATION OF DESOXYCORTICOSTERONE THERAPY IN CONGENITAL ADRENAL HYPERPLASIA

James F. Marks M.D.1 and Chester W. Fink M.D.1

1 The Department of Pediatrics, University of Texas Southwestern Medical School, Dallas

Three children with the salt-losing form of congenital adrenal hyperplasia developed hypertension during the course of therapy with desoxycorticosterone (DOC). The hypertension persisted for a much longer period of time than could be explained by the usual duration of the pharmacological action of the medication.

The three children received DOC trimethylacetate. In none could other causes of hypertension be implicated. No other cases of persistent hypertension in children related to DOC administration were found.

Submitted on November 3, 1966
Accepted on April 15, 1967




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R. L. Geggel, K. DeLuca, and D. B. Villee
Heart Failure Secondary to latrogenic Systemic Hypertension in an Infant with Congenital Adrenal Hyperplasia
Clinical Pediatrics, June 1, 1984; 23(6): 358 - 360.
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