PEDIATRICS Vol. 40 No. 1 July 1967, pp. 1-4
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PRIMARY DISORDERS OF THE SERUM LIPOPROTEINS IN CHILDHOOD

O. H. WOLFF M.D., F.R.C.P.1

1 Nuffield Professor of Child Health, Institute of Child Health, University of London, 30 Guildford Street, London, W. C. 1

ALL LIPIDS are transported in serum in association with proteins. These lipoprotein complexes can be separated by electrophoresis on paper or by ultracentrifugation. Paper electrophoresis is simple and can easily be introduced into any laboratory. In the fasting state two lipoprotein bands are seen: beta-lipoprotein, which has the mobility of beta globulin, and alpha-lipoprotein, which has the mobility of alpha1 globulin. Chylomicra, which appear after a fat containing meal, remain at the point of application of the serum to the paper; because it is situated at the opposite end of the strip to alpha-lipoprotein the chylomicron band has been named omega-lipoprotein.