PEDIATRICS Vol. 4 No. 4 October 1949, pp. 479-483
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MENINGITIS IN PREMATURE INFANTS

B. M. KAGAN M.D.1, J. H. HESS M.D.1, B. MIRMAN M.D.1, and EVELYN LUNDEEN R.N.1

1 The Kunstadter Laboratories for Pediatric Research and the Premature Station, Sarah Morris Hospital, Michael Reese Hospital, Chicago, Ill.

A review of the literature on the subject of meningitis in premature infants revealed 45 cases. In 10 of these cases from which bacterial agents were cultured, six showed a gram negative bacillus.

Twelve additional cases are added in this study and Esch. coli was cultured from the spinal fluid of nine (with another organism in three of the nine cases).

The symptoms and signs of meningitis in premature infants are discussed.

No reports have been found in the literature of recovery from meningitis in premature infants weighing less than 2,500 gm. The course and treatment of a premature infant who weighed less than 1,000 gm. and who recovered from an Esch. coli meningitis is described in detail.

Submitted on January 3, 1949




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