PEDIATRICS Vol. 4 No. 4 October 1949, pp. 412-417
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MIXED INFECTION OF HEMOLYTIC STREPTOCOCCI IN CASES OF PRIMARY TUBERCULOSIS IN CHILDREN

SVEN-IVAR ROLLOF M.D.1

1 The Pediatric Clinic of the Caroline Institute, Norrtulls Hospital, Stockholm, Sweden.

A survey of the literature on the occurrence of hemolytic streptococci and antistreptolysin in healthy subjects and on recent investigations of mixed infections in tuberculosis is discussed.

Among 190 cases of primary tuberculosis in children aged 1 to 15 years Str. hemolyticus were found in the pharynx and among 130 such cases antistreptolysin titers over 200 were found to be considerably more frequent than in healthy children or other healthy subjects.

Cases of primary tuberculosis where the symptom first manifested had been an eruption of erythema nodosum formed a special group, with a high frequency of streptococcal infection.

Cases with erythema nodosum or with a pathologically raised antistreptolysin or antistaphylolysin titer are given a course of penicillin.

Submitted on June 5, 1949