PEDIATRICS Vol. 39 No. 6 June 1967, pp. 931-934
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Polycystic Kidneys, Internal Hydrocephalus and Polydactylism in Newborn Siblings

ARTEMIS P. SIMOPOULOS M.D.1, GLORIA G. BRENNAN M.D.1, AFFAN ALWAN M.D., D.C.H.1, and NICHOLAS FIDIS M.D.1

1 Departments of Pediatrics and Pathology, The George Washington University, School of Medicine, 901 23rd Street, N.W., Washington, D.C. 20037

Three male siblings with polycystic kidney disease, internal hydrocephalus, and polydactylism are presented. These identical anomalies in three siblings constitute a new syndrome. It is recommended that future studies on polycystic kidney disease with central nervous system anomalies occurring in siblings should be reported in detail if the pathogenesis of the disease is to be understood.