PEDIATRICS Vol. 39 No. 4 April 1967, pp. 628-629
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Creatine Phosphokinase as an Indicator of Birth Trauma

J. GORDON MILLICHAP M.D.1

1 Division of Neurology, Children's Memorial Hospital, 2300 Children's Plaza, Chicago, Illinois 60614

In the article by Drs. Nathan Rudolph and Ruth T. Gross (Pediatrics, 38:1039, 1966), muscle damage is postulated as a likely cause for an increase in serum creatine phosphokinase (CPK) activity observed in some newborn infants following a complicated labor. The authors' introduction includes reference to CPK in nervous tissue, but brain trauma or anoxia as a possible factor in causation of the elevated serum CPK is not mentioned in discussion.