Professor Woolf has attempted to put together in this book a diverse group of 20 clinical syndromes which have in common some change in concentration of substances normally present in the urine. Each of these abnormalities is then identified, according to the compound present, as a specific renal dysfunction. This classification, convenient for historical description, was derived from a review of some 387 references from the English, French, and American literature. Very clear accounts are presented of cystinuria, galactosemia, Wilson's disease, hepatorenal syndrome, and renal hypoelectrolytemia (Bartter's syndrome).