PEDIATRICS Vol. 39 No. 2 February 1967, pp. 289-291
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The Lack of Association Between the Appearance of Complement Fixing Antibodies and the Recovery of Virus in a Child with Congenital Rubella

GILLES R. G. MONIF M.D.1, JANET H. HARDY M.D.2, and JOHN L. SEVER M.D., PH.D.3

1 Department of Pathology, Bellevue Hospital, New York, New York 10016
2 Associate Professor, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, Maryland 21205
3 Section on Infectious Diseases, Perinatal Research Branch, National Institute of Neurological, Diseases and Blindness and Laboratory on Infectious Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20014

A case of congenitally acquired infection with rubella virus was studied longitudinally with virological and serological specimens. The appearance of specific complement fixing activity in the infant's serum was not associated with an alteration in the pattern of recovery of rubella virus.