PEDIATRICS Vol. 39 No. 1 January 1967, pp. 146
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Letters to the Editor

ARNOLD P. GOLD M.D.1

1 Assistant Professor of Neurology, College of Physicians and Surgeons of Columbia University, New York, New York 10032

It is hoped that Dr. García's letter further stresses the importance of depigmented nevi in the diagnosis of tuberous sclerosis.

The article referred to in his letter discussed in detail the classic triad of tuberous sclerosis with retardation, adenoma sebaceum, and seizures. The authors stressed the high frequency of depigmented nevi. There was no statement concerning a possible relationship between these lesions and infantile spasms. This article failed to state when the depigmented lesions occurred, and the only reference was that depigmented nevi, café-au-lait spots, and subcutaneous nodules were present in addition to the adenoma sebaceum.